Gut Microbiota and Liver Transplantation: Immune Mechanisms behind the Rejection

نویسندگان

چکیده

Liver transplantation (LT) is the treatment of choice for patients with cirrhosis, decompensated disease, acute liver failure, and hepatocellular carcinoma (HCC). In 3–25% cases, an alarming problem chronic cellular rejection after LT, this event can lead to need new or death patient. On other hand, gut microbiota involved in several mechanisms sustaining model “gut–liver axis”. These include modulation immune response, which altered case dysbiosis, possibly resulting graft rejection. Some studies have evaluated composition cirrhotic before but few them assessed its impact on This review underlines changes transplantation, hypothesizing possible linking dysbiosis Evaluation these therefore essential order monitor success LT eventually adopt appropriate preventive measures.

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ژورنال

عنوان ژورنال: Biomedicines

سال: 2023

ISSN: ['2227-9059']

DOI: https://doi.org/10.3390/biomedicines11071792